Rabbit anti-Human CDY1B Polyclonal Antibody

Uniprot Id

Q9Y6F8

Target Species

Human

Target Name

CDY1

Target Full Name

Testis-specific chromodomain protein Y 1

Target Function

Has histone acetyltransferase activity, with a preference for histone H4.

Target Subcellular Location

Nucleus.

Target Tissue Specificity

Testis-specific. Detected in spermatids (at protein level).

Target Synonyms

CDY1; CDY1A;; CDY1BTestis-specific chromodomain protein Y 1; EC 2.3.1.48

Target Background

This gene encodes a protein containing a chromodomain and a histone acetyltransferase catalytic domain. Chromodomain proteins are components of heterochromatin-like complexes and can act as gene repressors. This protein is localized to the nucleus of late spermatids where histone hyperacetylation takes place. Histone hyperacetylation is thought to facilitate the transition in which protamines replace histones as the major DNA-packaging protein. The human chromosome Y has two identical copies of this gene within a palindromic region; this record represents the more centromeric copy. Chromosome Y also contains a pair of closely related genes in another more telomeric palindrome as well as several related pseudogenes. Two protein isoforms are encoded by transcript variants of this gene. Additional transcript variants have been described, but their full-length nature has not been determined.