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The antibody against CEACAM7 was raised in rabbit using the Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 7 protein (36-242AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CEACAM7 was raised in rabbit using the Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 7 protein (36-242AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon cancer using CEACAM7 Antibody at dilution of 1:100
| Cat.No | ADC-22177A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CEACAM7 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 7 protein (36-242AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q14002 |
Uniprot Id
Q14002
Target Species
Human
Target Name
CEACAM7
Target Full Name
Cell adhesion molecule CEACAM7
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor. Apical cell membrane.
Target Protein Families
Immunoglobulin superfamily, CEA family
Target Tissue Specificity
Expressed in columnar epithelial cells of the colon (at protein level). Strongly down-regulated in colonic adenocarcinomas.
Target Research Area
Tags & Cell Markers
Target Synonyms
Carcinoembryonic antigen CGM 2; Carcinoembryonic antigen CGM2; Carcinoembryonic antigen gene family member 2; Carcinoembryonic antigen related cell adhesion molecule 7; Carcinoembryonic antigen-related cell adhesion molecule 7; CEA; CEACAM 7; CEACAM7; CEAM7_HUMAN; CGM 2; CGM2
Target Background
This gene encodes a cell surface glycoprotein and member of the carcinoembryonic antigen (CEA) family of proteins. Expression of this gene may be downregulated in colon and rectal cancer. Additionally, lower expression levels of this gene may be predictive of rectal cancer recurrence. This gene is present in a CEA family gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants.
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