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The antibody against CEACAM8 was raised in rabbit using the Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8 protein (35-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against CEACAM8 was raised in rabbit using the Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8 protein (35-320AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon tissue using CEACAM8 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using CEACAM8 Antibody at dilution of 1:1002
| Cat.No | ADC-40475A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CEACAM8 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Carcinoembryonic antigen-related cell adhesion molecule 8 protein (35-320AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P31997 |
Uniprot Id
P31997
Target Species
Human
Target Name
CEACAM8
Target Full Name
Cell adhesion molecule CEACAM8
Target Function
Cell surface glycoprotein that plays a role in cell adhesion in a calcium-independent manner. Mediates heterophilic cell adhesion with other carcinoembryonic antigen-related cell adhesion molecules, such as CEACAM6. Heterophilic interaction with CEACAM8 occurs in activated neutrophils.
Target Subcellular Location
Cell membrane; Lipid-anchor, GPI-anchor. Cell surface.
Target Protein Families
Immunoglobulin superfamily, CEA family
Target Tissue Specificity
Expressed in leukocytes of chronic myeloid Leukemia patients and bone marrow.
Target Research Area
Immunology
Target Synonyms
Carcinoembryonic antigen CGM6; Carcinoembryonic antigen gene family member 6; Carcinoembryonic antigen related cell adhesion molecule 8; Carcinoembryonic antigen-related cell adhesion molecule 8; CD 66b; CD 67; CD66b; CD66b antigen; CD67; CD67 antigen; CEACAM 8; CEACAM8; CEAM8_HUMAN; CGM 6; CGM6; NCA 95; NCA95; Non-specific cross-reacting antigen NCA-95; Nonspecific cross reacting antigen NCA 95; Nonspecific cross reacting antigen NCA95
Target Background
Enables protein heterodimerization activity. Involved in heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules. Located in cell surface and extracellular space. Biomarker of severe acute respiratory syndrome.
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