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The antibody against CELF5 was raised in rabbit using the Human BRUNOL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against CELF5 was raised in rabbit using the Human BRUNOL5 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-49118A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CELF5 |
| Target Synonyms | CELF5 antibody; BRUNOL5CUGBP Elav-like family member 5 antibody; CELF-5 antibody; Bruno-like protein 5 antibody; CUG-BP- and ETR-3-like factor 5 antibody; RNA-binding protein BRUNOL-5 antibody | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human BRUNOL5 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N6W0 |
Uniprot Id
Q8N6W0
Target Species
Human
Target Name
CELF5
Target Full Name
CUGBP Elav-like family member 5
Target Function
RNA-binding protein implicated in the regulation of pre-mRNA alternative splicing. Mediates exon inclusion and/or exclusion in pre-mRNA that are subject to tissue-specific and developmentally regulated alternative splicing. Specifically activates exon 5 inclusion of cardiac isoforms of TNNT2 during heart remodeling at the juvenile to adult transition. Binds to muscle-specific splicing enhancer (MSE) intronic sites flanking the alternative exon 5 of TNNT2 pre-mRNA.
Target Subcellular Location
Nucleus. Cytoplasm.
Target Protein Families
CELF/BRUNOL family
Target Tissue Specificity
Expressed in brain.
Target Synonyms
CELF5; BRUNOL5CUGBP Elav-like family member 5; CELF-5; Bruno-like protein 5; CUG-BP- and ETR-3-like factor 5; RNA-binding protein BRUNOL-5
Target Background
This gene encodes a member of the the CELF/BRUNOL protein family, which contain two N-terminal RNA recognition motif (RRM) domains, one C-terminal RRM domain, and a divergent segment of 160-230 aa between the second and third RRM domains. Members of this protein family regulate pre-mRNA alternative splicing and may also be involved in mRNA editing and translation. Alternatively spliced transcript variants have been found for this gene.
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