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The antibody against CGN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 904-1203 of human CGN (NP_065821.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against CGN was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 904-1203 of human CGN (NP_065821.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-10089A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CGN |
| Target Synonyms | CGN; cingulin | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | 293T, A-549, BxPC-3, LO2 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 904-1203 of human CGN (NP_065821.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9P2M7 | Immunogen Sequence |
Uniprot Id
Q9P2M7
Target Species
Human
Target Name
CGN
Target Full Name
Cingulin
Target Function
Probably plays a role in the formation and regulation of the tight junction (TJ) paracellular permeability barrier.
Target Subcellular Location
Cell junction, tight junction.
Target Protein Families
Cingulin family
Target Tissue Specificity
Localized on the cytoplasmic face of tight junctions of polarized epithelia and some endothelia. Expressed in pancreas, kidney, liver and lung, but not in skeletal muscle, placenta, brain or heart.
Target Synonyms
6330408J11Rik; AI647528; AI987749; cgn; CING_HUMAN; Cingulin; DKFZp779N1112; FLJ39281; KIAA1319; MGC118157
Target Background
Enables cadherin binding activity. Predicted to act upstream of or within bicellular tight junction assembly; epithelial cell morphogenesis; and microtubule cytoskeleton organization. Located in bicellular tight junction and plasma membrane.
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