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The antibody against CHI3L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-390 of human CHI3L2 (NP_003991.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against CHI3L2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 27-390 of human CHI3L2 (NP_003991.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-02388A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHI3L2 |
| Target Synonyms | CHIL2; YKL39; YKL-39; CHI3L2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Jurkat | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 27-390 of human CHI3L2 (NP_003991.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q15782 | Immunogen Sequence |
Uniprot Id
Q15782
Target Species
Human
Target Name
CHI3L2
Target Full Name
Chitinase-3-like protein 2
Target Function
Lectin that binds chitooligosaccharides and other glycans with high affinity, but not heparin. Has no chitinase activity.
Target Subcellular Location
Secreted.
Target Protein Families
Glycosyl hydrolase 18 family
Target Tissue Specificity
Highest expression in chondrocytes, followed by synoviocytes, lung and heart. Not detected in spleen, pancreas, and liver. May also be expressed in developing brain and placenta.
Target Synonyms
CH3L2_HUMAN; CHI3L2; Chitinase 3 like 2; Chitinase-3-like protein 2; Chondrocyte protein 39; OTTHUMP00000014028; YKL 39; YKL-39; YKL39
Target Background
The protein encoded by this gene is similar to bacterial chitinases but lacks chitinase activity. The encoded protein is secreted and is involved in cartilage biogenesis. Several transcript variants encoding different isoforms have been found for this gene.
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