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The antibody against CHKA was raised in rabbit using the Recombinant Human Choline kinase alpha protein (79-173AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against CHKA was raised in rabbit using the Recombinant Human Choline kinase alpha protein (79-173AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC, IF.
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Immunohistochemistry of paraffin-embedded human lung cancer using CHKA Antibody at dilution of 1:1002
| Cat.No | ADC-08622A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHKA |
| Target Synonyms | CHKA antibody; CHK antibody; CKI antibody; Choline kinase alpha antibody; CK antibody; EC 2.7.1.32 antibody; CHETK-alpha antibody; Ethanolamine kinase antibody; EK antibody; EC 2.7.1.82 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IF, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Choline kinase alpha protein (79-173AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P35790 |
Uniprot Id
P35790
Target Species
Human
Target Name
CHKA
Target Full Name
Choline kinase alpha
Target Function
Has a key role in phospholipid biosynthesis and may contribute to tumor cell growth. Catalyzes the first step in phosphatidylcholine biosynthesis. Contributes to phosphatidylethanolamine biosynthesis. Phosphorylates choline and ethanolamine. Has higher activity with choline.
Target Subcellular Location
Cytoplasm.
Target Protein Families
Choline/ethanolamine kinase family
Target Synonyms
CHKA; CHK; CKI; Choline kinase alpha; CK; EC 2.7.1.32; CHETK-alpha; Ethanolamine kinase; EK; EC 2.7.1.82
Target Background
The major pathway for the biosynthesis of phosphatidylcholine occurs via the CDP-choline pathway. The protein encoded by this gene is the initial enzyme in the sequence and may play a regulatory role. The encoded protein also catalyzes the phosphorylation of ethanolamine. Two transcript variants encoding different isoforms have been found for this gene.
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