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The antibody against CHMP7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 230-453 of human CHMP7 (NP_689485.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CHMP7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 230-453 of human CHMP7 (NP_689485.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-10214A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHMP7 |
| Target Synonyms | CHMP7 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Rat brain, Jurkat, Mouse brain, Mouse testis | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 230-453 of human CHMP7 (NP_689485.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8WUX9 | Immunogen Sequence |
Uniprot Id
Q8WUX9
Target Species
Human
Target Name
CHMP7
Target Full Name
Charged multivesicular body protein 7
Target Function
ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope during late anaphase. Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase. Plays a role in the endosomal sorting pathway.
Target Subcellular Location
Cytoplasm. Nucleus envelope.
Target Protein Families
SNF7 family
Target Research Area
Signal Transduction
Target Synonyms
CHMP7Charged multivesicular body protein 7; Chromatin-modifying protein 7
Target Background
Involved in several processes, including late endosome to vacuole transport; midbody abscission; and mitotic nuclear division. Located in cytosol; nuclear envelope; and nucleoplasm. Part of ESCRT III complex. Colocalizes with chromatin.
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