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The antibody against CHN2 was raised in rabbit using the Recombinant Human Beta-chimaerin protein (1-91AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CHN2 was raised in rabbit using the Recombinant Human Beta-chimaerin protein (1-91AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-06951A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHN2 |
| Target Synonyms | CHN2 antibody; ARHGAP3 antibody; BCH antibody; Beta-chimaerin antibody; Beta-chimerin antibody; Rho GTPase-activating protein 3 antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Beta-chimaerin protein (1-91AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P52757 |
Uniprot Id
P52757
Target Species
Human
Target Name
CHN2
Target Full Name
Beta-chimaerin
Target Function
GTPase-activating protein for p21-rac. Insufficient expression of beta-2 chimaerin is expected to lead to higher Rac activity and could therefore play a role in the progression from low-grade to high-grade tumors.
Target Subcellular Location
Membrane; Peripheral membrane protein.
Target Tissue Specificity
Highest levels in the brain and pancreas. Also expressed in the heart, placenta, and weakly in the kidney and liver. Expression is much reduced in the malignant gliomas, compared to normal brain or low-grade astrocytomas.
Target Synonyms
CHN2; ARHGAP3; BCH; Beta-chimaerin; Beta-chimerin; Rho GTPase-activating protein 3
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