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The antibody against CHPF was raised in rabbit using the Synthesized peptide derived from internal of Human CHSS2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against CHPF was raised in rabbit using the Synthesized peptide derived from internal of Human CHSS2. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC, IF.
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Western blot analysis of extracts from LOVO cells and K562 cells, using CHSS2 antibody.
Immunohistochemistry analysis of paraffin-embedded human cervix carcinoma tissue using CHSS2 antibody.2
Immunofluorescence analysis of MCF-7 cells, using CHSS2 antibody.3
| Cat.No | ADC-41323A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHPF |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from internal of Human CHSS2. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8IZ52 |
Uniprot Id
Q8IZ52
Target Species
Human
Target Name
CHPF
Target Full Name
Chondroitin sulfate synthase 2
Target Function
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Isoform 2 may facilitate PRKN transport into the mitochondria. In collaboration with PRKN, isoform 2 may enhance cell viability and protect cells from oxidative stress.
Target Subcellular Location
[Isoform 1]: Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Cytoplasm, cytosol.; [Isoform 3]: Cytoplasm, cytosol. Mitochondrion.; [Isoform 2]: Mitochondrion matrix.
Target Protein Families
Chondroitin N-acetylgalactosaminyltransferase family
Target Tissue Specificity
Ubiquitous. Highly expressed in pancreas, ovary, brain, heart, skeletal muscle, colon, kidney, liver, stomach, spleen and placenta. Isoform 3 is also ubiquitous. Isoform 2 is expressed in brain, spleen, ovary, testis, lung and peripheral mononuclear cells
Target Synonyms
CHPF; CSS2; UNQ651/PRO1281Chondroitin sulfate synthase 2; EC 2.4.1.175; EC 2.4.1.226; Chondroitin glucuronyltransferase 2; Chondroitin-polymerizing factor; ChPF; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase II; N-acetylgalactosaminyltransferase 2
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