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The antibody against CHRDL2 was raised in rabbit using the Synthetic peptide of Human CHRDL2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against CHRDL2 was raised in rabbit using the Synthetic peptide of Human CHRDL2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
$299.00
| Cat.No | ADC-26910A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHRDL2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Synthetic peptide of Human CHRDL2 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q6WN34 |
Uniprot Id
Q6WN34
Target Species
Human
Target Name
CHRDL2
Target Full Name
Chordin-like protein 2
Target Function
May inhibit BMPs activity by blocking their interaction with their receptors. Has a negative regulator effect on the cartilage formation/regeneration from immature mesenchymal cells, by preventing or reducing the rate of matrix accumulation. Implicated in tumor angiogenesis. May play a role during myoblast and osteoblast differentiation, and maturation.
Target Subcellular Location
[Isoform 1]: Secreted.; [Isoform 2]: Secreted.; [Isoform 3]: Cytoplasm.; [Isoform 4]: Cytoplasm.; [Isoform 5]: Cytoplasm.
Target Tissue Specificity
Highly expressed in uterus. Moderately expressed in heart, liver, prostate, testis and ovary. Weakly expressed in skeletal muscle, kidney, spleen, small intestine and colon. Expressed in the secretory epithelial cells of uterine endometrium, fallopian tub
Target Synonyms
BNF-1; BNF1 ; Breast tumor novel factor 1; CHL2 ; chordin like 2; Chordin like protein 2 precursor ; Chordin related protein 2; Chordin-like protein 2; Chordin-related protein 2; Chrdl2; CRDL2_HUMAN; DKFZp586N2124; FKSG37
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