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The antibody against CHSY1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CHSY1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
The antibody against CHSY1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CHSY1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.
$167.00
Western Blot analysis of K562 cells using CHSY1 Polyclonal Antibody
| Cat.No | ADC-39019A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CHSY1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human CHSY1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q86X52 |
Uniprot Id
Q86X52
Target Species
Human
Target Name
CHSY1
Target Full Name
Chondroitin sulfate synthase 1
Target Function
Has both beta-1,3-glucuronic acid and beta-1,4-N-acetylgalactosamine transferase activity. Transfers glucuronic acid (GlcUA) from UDP-GlcUA and N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of the elongating chondroitin polymer. Involved in the negative control of osteogenesis likely through the modulation of NOTCH signaling.
Target Involvement
Temtamy preaxial brachydactyly syndrome (TPBS)
Target Subcellular Location
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted.
Target Protein Families
Chondroitin N-acetylgalactosaminyltransferase family
Target Tissue Specificity
Ubiquitous, with the highest levels in placenta. Detected at low levels in brain, heart, skeletal muscle, colon, thymus, spleen, kidney, liver, adrenal gland, mammary gland, stomach, small intestine, lung and peripheral blood leukocytes.
Target Synonyms
Carbohydrate synthase 1; Chondroitin glucuronyltransferase 1; Chondroitin glucuronyltransferase II; Chondroitin sulfate synthase 1; Chondroitin synthase 1; CHSS1_HUMAN; CHSY; ChSy-1; Chsy1; CSS1; Glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase 1; N acetylgalactosaminyltransferase II; N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase 1; N-acetylgalactosaminyltransferase 1; TPBS
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