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The antibody against CISD1 was raised in rabbit using the Human mitoNEET,CISD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
The antibody against CISD1 was raised in rabbit using the Human mitoNEET,CISD1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.
$600.00
| Cat.No | ADC-51207A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CISD1 |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat, Zebrafish |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human mitoNEET,CISD1 | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9NZ45 |
Uniprot Id
Q9NZ45
Target Species
Human
Target Name
CISD1
Target Full Name
CDGSH iron-sulfur domain-containing protein 1
Target Function
Plays a key role in regulating maximal capacity for electron transport and oxidative phosphorylation. May be involved in Fe-S cluster shuttling and/or in redox reactions.
Target Subcellular Location
Mitochondrion outer membrane; Single-pass type III membrane protein.
Target Protein Families
CISD protein family
Target Tissue Specificity
Expression is reduced in cells derived from cystic fibrosis patients.
Target Synonyms
AU043990; AW743335; C10orf70; CDGSH iron sulfur domain 1; CDGSH iron-sulfur domain-containing protein 1; CISD 1; CISD1; CISD1_HUMAN; D10Ertd214e; MDS029; MGC14684; MitoNEET; RGD1309529; ZCD1; Zinc finger CDGSH type domain 1
Target Background
This gene encodes a protein with a CDGSH iron-sulfur domain and has been shown to bind a redox-active [2Fe-2S] cluster. The encoded protein has been localized to the outer membrane of mitochondria and is thought to play a role in regulation of oxidation. Genes encoding similar proteins are located on chromosomes 4 and 17, and a pseudogene of this gene is located on chromosome 2.
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