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The antibody against CKLF was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human C32. as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against CKLF was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human C32. as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
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Western blot analysis of 3T3 lysis using CKLF antibody.. Secondary antibody was diluted at 1:20000
| Cat.No | ADC-13131A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CKLF |
| Target Synonyms | CKLF; CKLF1; HSPC224; UNQ410/PRO772; Chemokine-like factor; C32 | Form | Liquid |
| Species Reactivity | Human | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the C-terminal region of Human C32. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9UBR5 |
Uniprot Id
Q9UBR5
Target Species
Human
Target Name
CKLF
Target Full Name
Chemokine-like factor
Target Function
May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10.; has chemotactic response in monocytes, neutrophils and lymphocytes. Binds CCR4.
Target Subcellular Location
[Isoform 1]: Secreted.; [Isoform 2]: Membrane; Multi-pass membrane protein.; [Isoform 4]: Membrane; Multi-pass membrane protein.
Target Protein Families
Chemokine-like factor family
Target Tissue Specificity
Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skel
Target Synonyms
CKLF; CKLF1; HSPC224; UNQ410/PRO772; Chemokine-like factor; C32
Target Background
The product of this gene is a cytokine. Cytokines are small proteins that have an essential role in the immune and inflammatory responses. This gene is one of several chemokine-like factor genes located in a cluster on chromosome 16. The protein encoded by this gene is a potent chemoattractant for neutrophils, monocytes and lymphocytes. It also can stimulate the proliferation of skeletal muscle cells. This protein may play important roles in inflammation and in the regeneration of skeletal muscle. Alternatively spliced transcript variants encoding different isoforms have been identified. Naturally occurring read-through transcription occurs between this locus and the neighboring locus CMTM1 (CKLF-like MARVEL transmembrane domain containing 1).
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