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The antibody against CKM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 3-381 of human CKM (NP_001815.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
The antibody against CKM was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 3-381 of human CKM (NP_001815.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, ELISA.
| Cat.No | ADA-11318A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CKM |
| Target Synonyms | CKMM; M-CK; CPK-M; CKM | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse skeletal muscle | Application | ELISA, WB, IF/ICC |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 3-381 of human CKM (NP_001815.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P06732 | Immunogen Sequence |
Uniprot Id
P06732
Target Species
Human
Target Name
CKM
Target Full Name
Creatine kinase M-type
Target Function
Reversibly catalyzes the transfer of phosphate between ATP and various phosphogens (e.g. creatine phosphate). Creatine kinase isoenzymes play a central role in energy transduction in tissues with large, fluctuating energy demands, such as skeletal muscle, heart, brain and spermatozoa.
Target Subcellular Location
Cytoplasm.
Target Protein Families
ATP:guanido phosphotransferase family
Target Research Area
Cancer
Target Synonyms
(Creatine kinase M chain)(Creatine phosphokinase M-type)(CPK-M)(M-CK)
Target Background
The protein encoded by this gene is a cytoplasmic enzyme involved in energy homeostasis and is an important serum marker for myocardial infarction. The encoded protein reversibly catalyzes the transfer of phosphate between ATP and various phosphogens such as creatine phosphate. It acts as a homodimer in striated muscle as well as in other tissues, and as a heterodimer with a similar brain isozyme in heart. The encoded protein is a member of the ATP:guanido phosphotransferase protein family.
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