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Rabbit anti-Human CLDN2 Polyclonal Antibody

The antibody against CLDN2 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Claudin-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-33382A

The antibody against CLDN2 was raised in rabbit using the Synthesized peptide derived from the C-terminal region of Human Claudin-2. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-33382A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCLDN2
Target SynonymsCLDN2; PSEC0059; SP82; UNQ705/PRO1356; Claudin-2; SP82FormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the C-terminal region of Human Claudin-2.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP57739
Background Information
  • Uniprot Id

    P57739

  • Target Species

    Human

  • Target Name

    CLDN2

  • Target Full Name

    Claudin-2

  • Target Function

    Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity.

  • Target Subcellular Location

    Cell junction, tight junction. Cell membrane; Multi-pass membrane protein.

  • Target Protein Families

    Claudin family

  • Target Synonyms

    CLDN2; PSEC0059; SP82; UNQ705/PRO1356; Claudin-2; SP82

  • Target Background

    This gene product belongs to the claudin protein family whose members have been identified as major integral membrane proteins localized exclusively at tight junctions. Claudins are expressed in an organ-specific manner and regulate tissue-specific physiologic properties of tight junctions. This protein is expressed in the intestine. Alternatively spliced transcript variants with different 5' untranslated region have been found for this gene.

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