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The antibody against C1R was raised in rabbit using the Synthesized peptide derived from the Internal region of Human C1r LC. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
The antibody against C1R was raised in rabbit using the Synthesized peptide derived from the Internal region of Human C1r LC. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.
$167.00
Western Blot analysis of 293 cells using Cleaved-C1r LC (I464) Polyclonal Antibody
| Cat.No | ADC-39960A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | C1R |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human C1r LC. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P00736 |
Uniprot Id
P00736
Target Species
Human
Target Name
C1R
Target Full Name
Complement C1r subcomponent
Target Function
C1r B chain is a serine protease that combines with C1q and C1s to form C1, the first component of the classical pathway of the complement system.
Target Involvement
Ehlers-Danlos syndrome, periodontal type, 1 (EDSPD1)
Target Subcellular Location
Secreted.
Target Protein Families
Peptidase S1 family
Target Synonyms
C1 R; C1R; C1R_HUMAN; Complement C1r; Complement C1r subcomponent; Complement C1r subcomponent light chain; Complement C1r subcomponent precursor; Complement component 1 r subcomponent; Complement component 1 subcomponent r
Target Background
This gene encodes a member of the peptidase S1 protein family. The encoded protein is a proteolytic subunit in the complement system C1 complex. The complement system acts as a mediator in the innate immune response by ultimately triggering phagocytosis, inflammation, and rupturing the bacterial cell wall. Mutations in this gene are associated with Ehlers-Danlos Syndrome.
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