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Rabbit anti-Human CLEC11A Polyclonal Antibody

The antibody against CLEC11A was raised in rabbit using the Recombinant Human C-type lectin domain family 11 member A protein (22-323AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.

ADC-40473A

The antibody against CLEC11A was raised in rabbit using the Recombinant Human C-type lectin domain family 11 member A protein (22-323AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC, IF.

$299.00

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Specifications


Cat.No ADC-40473A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCLEC11A
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IF, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human C-type lectin domain family 11 member A protein (22-323AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ9Y240
Background Information
  • Uniprot Id

    Q9Y240

  • Target Species

    Human

  • Target Name

    CLEC11A

  • Target Full Name

    C-type lectin domain family 11 member A

  • Target Function

    Promotes osteogenesis by stimulating the differentiation of mesenchymal progenitors into mature osteoblasts. Important for repair and maintenance of adult bone.

  • Target Subcellular Location

    Cytoplasm. Secreted.

  • Target Tissue Specificity

    Expressed in skeletal tissues including bone marrow, chondrocytes, primary ossification center-associated cells, the perichondrium and periosteum. Lower levels of expression were detected in spleen, thymus, appendix and fetal liver.

  • Target Synonyms

    C type (calcium dependent; carbohydrate recognition domain) lectin; superfamily member 3; C type lectin domain family 11 member A; C type lectin superfamily member 3; C-type lectin domain family 11 member A; C-type lectin superfamily member 3; CLC11_HUMAN; CLEC11A; CLECSF3; LSLCL; Lymphocyte secreted C type lectin; Lymphocyte secreted C-type lectin; lymphocyte secreted long form of C type lectin; p47; Stem cell growth factor; stem cell growth factor lymphocyte secreted C type lectin

  • Target Background

    This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined.

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