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Rabbit anti-Human CLEC2A Polyclonal Antibody

The antibody against CLEC2A was raised in rabbit using the Synthetic peptide of Human CLEC2A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-28672A

The antibody against CLEC2A was raised in rabbit using the Synthetic peptide of Human CLEC2A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-28672A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCLEC2A
FormLiquidSpecies ReactivityHuman
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthetic peptide of Human CLEC2ATarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ6UVW9
Background Information
  • Uniprot Id

    Q6UVW9

  • Target Species

    Human

  • Target Name

    CLEC2A

  • Target Full Name

    C-type lectin domain family 2 member A

  • Target Function

    Plays a role in modulating the extent of T-cell expansion. Enhances the expansion of TCR-stimulated T-cells by increasing their survival through enhanced expression of anti-apoptotic proteins. May modulate the capacity of T-cells to home to lymph nodes through SELL. Facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity.

  • Target Subcellular Location

    Cell membrane; Single-pass type II membrane protein.

  • Target Tissue Specificity

    Mainly expressed in skin. Also expressed in keratinocytes, spleen, thymus, small intestine, peripheral blood monocytes, bone marrow, ovary, testis and skin. High expression in CD8(+), B-lymphocytes and naive CD4(+) T-cells. Restricted mostly to proliferat

  • Target Synonyms

    C-type lectin domain family 2 member A; CLC2A_HUMAN; CLEC2A; INPE5792; KACL; Keratinocyte-associated C-type lectin; PILAR; Proliferation-induced lymphocyte-associated receptor; UNQ5792

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