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The antibody against CLIC3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 87-236 of human CLIC3 (NP_004660.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CLIC3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 87-236 of human CLIC3 (NP_004660.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05125A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CLIC3 |
| Target Synonyms | CLIC3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, Mouse lung, Rat lung | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 87-236 of human CLIC3 (NP_004660.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | GPPDFPSLAPRYRESNTAGNDVFHKFSAFIKNPVPAQDEALYQQLLRALARLDSYLRAPLEHELAGEPQLRESRRRFLDGDRLTLADCSLLPKLHIVDTVCAHFRQAPIPAELRGVRRYLDSAMQEKEFKYTCPHSAEILAAYRPAVHPR | Uniprot ID | O95833 |
Uniprot Id
O95833
Target Species
Human
Target Name
CLIC3
Target Full Name
Chloride intracellular channel protein 3
Target Function
Can insert into membranes and form chloride ion channels. May participate in cellular growth control.
Target Subcellular Location
Nucleus. Membrane; Single-pass membrane protein. Cytoplasm.
Target Protein Families
Chloride channel CLIC family
Target Tissue Specificity
Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas.
Target Synonyms
CLIC3; Chloride intracellular channel protein 3
Target Background
Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.
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