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Rabbit anti-Human CLIC3 Polyclonal Antibody

The antibody against CLIC3 was raised in rabbit using the Human CLIC3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

ADC-53766A

The antibody against CLIC3 was raised in rabbit using the Human CLIC3 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC, IF.

$600.00

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Specifications


Cat.No ADC-53766A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCLIC3
Target SynonymsCLIC3; Chloride intracellular channel protein 3FormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.02% sodium azidePurification MethodAntigen affinity purified
ConjugateNon-conjugatedApplicationELISA, IF, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman CLIC3Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO95833
Background Information
  • Uniprot Id

    O95833

  • Target Species

    Human

  • Target Name

    CLIC3

  • Target Full Name

    Chloride intracellular channel protein 3

  • Target Function

    Can insert into membranes and form chloride ion channels. May participate in cellular growth control.

  • Target Subcellular Location

    Nucleus. Membrane; Single-pass membrane protein. Cytoplasm.

  • Target Protein Families

    Chloride channel CLIC family

  • Target Tissue Specificity

    Detected in placenta (at protein level). Widely expressed. High expression is found in placenta followed by lung and heart. Low expression in skeletal muscle, kidney and pancreas.

  • Target Synonyms

    CLIC3; Chloride intracellular channel protein 3

  • Target Background

    Chloride channels are a diverse group of proteins that regulate fundamental cellular processes including stabilization of cell membrane potential, transepithelial transport, maintenance of intracellular pH, and regulation of cell volume. Chloride intracellular channel 3 is a member of the p64 family and is predominantly localized in the nucleus and stimulates chloride ion channel activity. In addition, this protein may participate in cellular growth control, based on its association with ERK7, a member of the MAP kinase family.

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