Rabbit anti-Human CLIP1 Polyclonal Antibody

The antibody against CLIP1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1228-1427 of human CLIP1 (NP_002947.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-06350A

Number

Cat.No	ADA-06350A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	CLIP1
Target Synonyms	RSN; CLIP; CYLN1; CLIP170; CLIP-170; CLIP1	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse heart, U-87MG	Application	ELISA, WB

Cat.No

ADA-06350A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

CLIP1

Target Synonyms

RSN; CLIP; CYLN1; CLIP170; CLIP-170; CLIP1

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse heart, U-87MG

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1228-1427 of human CLIP1 (NP_002947.1).	Target Species	Human
Immunogen Sequence	SALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLFCDICDCFDLHDTEDCPTQAQMSEDPPHSTHHGSRGEERPYCEICEMFGHWATNCNDDETF	Uniprot ID	P30622

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1228-1427 of human CLIP1 (NP_002947.1).

Target Species

Human

Immunogen Sequence

SALLTEKDAELEKLRNEVTVLRGENASAKSLHSVVQTLESDKVKLELKVKNLELQLKENKRQLSSSSGNTDTQADEDERAQESQIDFLNSVIVDLQRKNQDLKMKVEMMSEAALNGNGDDLNNYDSDDQEKQSKKKPRLFCDICDCFDLHDTEDCPTQAQMSEDPPHSTHHGSRGEERPYCEICEMFGHWATNCNDDETF

Uniprot ID

P30622

Background Information

Uniprot Id

P30622
Target Species

Human
Target Name

CLIP1
Target Full Name

CAP-Gly domain-containing linker protein 1
Target Function

Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking.
Target Subcellular Location

Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle.
Target Tissue Specificity

Detected in dendritic cells (at protein level). Highly expressed in the Reed-Sternberg cells of Hodgkin disease.
Target Synonyms

CAP GLY domain containing linker protein 1; CAP-Gly domain-containing linker protein 1; CLIP 170; CLIP; CLIP-170; CLIP1; CLIP1_HUMAN; CYLN1; cytoplasmic linker 1; Cytoplasmic linker protein 1; Cytoplasmic linker protein 170 alpha 2; Cytoplasmic linker protein 170 alpha-2; Cytoplasmic linker protein CLIP 170; Reed Steinberg cell expressed intermediate filament associated; Reed Sternberg intermediate filament associated protein 3; Reed-Sternberg intermediate filament-associated protein; Restin; RSN
Target Background

The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene.

Rabbit anti-Human CLIP1 Polyclonal Antibody

Specifications

Immunogen Information

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