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Rabbit anti-Human CLIP1 Polyclonal Antibody

The antibody against CLIP1 was raised in rabbit using the Fusion protein of Human CLIP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

ADC-30332A

The antibody against CLIP1 was raised in rabbit using the Fusion protein of Human CLIP1 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.

$299.00

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Specifications


Cat.No ADC-30332A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCLIP1
FormLiquidSpecies ReactivityHuman, Mouse
IsotypeIgGStorage Buffer0.05% NaN3, 40% Glycerol., pH7.4 PBS
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHCStorageUpon receipt

Immunogen Information


Immunogen DescriptionFusion protein of Human CLIP1Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP30622
Background Information
  • Uniprot Id

    P30622

  • Target Species

    Human

  • Target Name

    CLIP1

  • Target Full Name

    CAP-Gly domain-containing linker protein 1

  • Target Function

    Binds to the plus end of microtubules and regulates the dynamics of the microtubule cytoskeleton. Promotes microtubule growth and microtubule bundling. Links cytoplasmic vesicles to microtubules and thereby plays an important role in intracellular vesicle trafficking. Plays a role macropinocytosis and endosome trafficking.

  • Target Subcellular Location

    Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell projection, ruffle.

  • Target Tissue Specificity

    Detected in dendritic cells (at protein level). Highly expressed in the Reed-Sternberg cells of Hodgkin disease.

  • Target Synonyms

    CAP GLY domain containing linker protein 1; CAP-Gly domain-containing linker protein 1; CLIP 170; CLIP; CLIP-170; CLIP1; CLIP1_HUMAN; CYLN1; cytoplasmic linker 1; Cytoplasmic linker protein 1; Cytoplasmic linker protein 170 alpha 2; Cytoplasmic linker protein 170 alpha-2; Cytoplasmic linker protein CLIP 170; Reed Steinberg cell expressed intermediate filament associated; Reed Sternberg intermediate filament associated protein 3; Reed-Sternberg intermediate filament-associated protein; Restin; RSN

  • Target Background

    The protein encoded by this gene links endocytic vesicles to microtubules. This gene is highly expressed in Reed-Sternberg cells of Hodgkin disease. Several transcript variants encoding different isoforms have been found for this gene.

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