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Rabbit anti-Human CMIP Polyclonal Antibody

The antibody against CMIP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 640-773 of human CMIP (NP_938204.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-03809A

The antibody against CMIP was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 640-773 of human CMIP (NP_938204.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

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Specifications


Cat.No ADA-03809A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCMIP
Target SynonymsTCMIP; CMIPFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.05% proclin300, pH7.3.Purification MethodAffinity purification
Positive SamplesMouse kidney, K-562, Mouse testis, Rat kidneyApplicationELISA, WB, IHC-P

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 640-773 of human CMIP (NP_938204.2).Target SpeciesHuman
Immunogen SequenceRLTLPSKSTDADLARLLSSGSFGNLENLSLAFTNVTSACAEHLIKLPSLKQLNLWSTQFGDAGLRLLSEHLTMLQVLNLCETPVTDAGLLALSSMKSLCSLNMNSTKLSADTYEDLKAKLPNLKEVDVRYTEAWUniprot IDQ8IY22
Background Information
  • Uniprot Id

    Q8IY22

  • Target Species

    Human

  • Target Name

    CMIP

  • Target Full Name

    C-Maf-inducing protein

  • Target Function

    Plays a role in T-cell signaling pathway. Isoform 2 may play a role in T-helper 2 (Th2) signaling pathway and seems to represent the first proximal signaling protein that links T-cell receptor-mediated signal to the activation of c-Maf Th2 specific factor.

  • Target Subcellular Location

    Nucleus. Cytoplasm.

  • Target Tissue Specificity

    Isoform 1 is expressed in peripheral blood mononuclear cells and kidney. Lower expression in brain and liver. Expression is down-regulated in activated cells. Isoform 2 is expressed in lymphocyte precursors, however, expression shuts down during maturatio

  • Target Synonyms

    TCMIP; CMIP

  • Target Background

    This gene encodes a c-Maf inducing protein that plays a role in T-cell signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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