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The antibody against CNKSR2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 400-750 of human CNKSR2 (NP_055742.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CNKSR2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 400-750 of human CNKSR2 (NP_055742.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-05561A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CNKSR2 |
| Target Synonyms | CNK2; KSR2; MAGUIN; MRXSHG; CNKSR2 | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HepG2, Jurkat, U-87MG | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 400-750 of human CNKSR2 (NP_055742.2). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q8WXI2 | Immunogen Sequence |
Uniprot Id
Q8WXI2
Target Species
Human
Target Name
CNKSR2
Target Full Name
Connector enhancer of kinase suppressor of ras 2
Target Function
May function as an adapter protein or regulator of Ras signaling pathways.
Target Subcellular Location
Cytoplasm. Membrane; Peripheral membrane protein.
Target Protein Families
CNKSR family
Target Research Area
Signal Transduction
Target Synonyms
CNKSR2; CNK2; KIAA0902; KSR2Connector enhancer of kinase suppressor of ras 2; Connector enhancer of KSR 2; CNK homolog protein 2; CNK2
Target Background
This gene encodes a multidomain protein that functions as a scaffold protein to mediate the mitogen-activated protein kinase pathways downstream from Ras. This gene product is induced by vitamin D and inhibits apoptosis in certain cancer cells. It may also play a role in ternary complex assembly of synaptic proteins at the postsynaptic membrane and coupling of signal transduction to membrane/cytoskeletal remodeling. Multiple transcript variants encoding different isoforms have been found for this gene.
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