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Rabbit anti-Human CNOT9 Polyclonal Antibody

The antibody against CNOT9 was raised in rabbit using the Recombinant Human CCR4-NOT transcription complex subunit 9 protein (1-258AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

ADC-23752A

The antibody against CNOT9 was raised in rabbit using the Recombinant Human CCR4-NOT transcription complex subunit 9 protein (1-258AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, WB, IHC.

$299.00

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Specifications


Cat.No ADC-23752A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCNOT9
Target SynonymsCNOT9 antibody; RCD1 antibody; RQCD1CCR4-NOT transcription complex subunit 9 antibody; Cell differentiation protein RQCD1 homolog antibody; Rcd-1 antibodyFormLiquid
Species ReactivityHuman, MouseIsotypeIgG
Storage Buffer0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4Purification Method>95%, Protein G purified
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionRecombinant Human CCR4-NOT transcription complex subunit 9 protein (1-258AA)Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDQ92600
Background Information
  • Uniprot Id

    Q92600

  • Target Species

    Human

  • Target Name

    CNOT9

  • Target Full Name

    CCR4-NOT transcription complex subunit 9

  • Target Function

    Component of the CCR4-NOT complex which is one of the major cellular mRNA deadenylases and is linked to various cellular processes including bulk mRNA degradation, miRNA-mediated repression, translational repression during translational initiation and general transcription regulation. Additional complex functions may be a consequence of its influence on mRNA expression. Involved in down-regulation of MYB- and JUN-dependent transcription. May play a role in cell differentiation. Can bind oligonucleotides, such as poly-G, poly-C or poly-T (in vitro), but the physiological relevance of this is not certain. Does not bind poly-A. Enhances ligand-dependent transcriptional activity of nuclear hormone receptors, including RARA, expect ESR1-mediated transcription that is not only slightly increased, if at all.

  • Target Subcellular Location

    Nucleus. Cytoplasm, P-body.

  • Target Protein Families

    CNOT9 family

  • Target Tissue Specificity

    Detected in spleen, thymus, prostate, testis, ovary and intestine.

  • Target Synonyms

    CNOT9; RCD1; RQCD1CCR4-NOT transcription complex subunit 9; Cell differentiation protein RQCD1 homolog; Rcd-1

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