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Rabbit anti-Human CNTROB Polyclonal Antibody

The antibody against CNTROB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 604-903 of human CNTROB (NP_444279.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-01545A

The antibody against CNTROB was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 604-903 of human CNTROB (NP_444279.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

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Specifications


Cat.No ADA-01545A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCNTROB
Target SynonymsLIP8; PP1221; CNTROBFormLiquid
Species ReactivityHumanIsotypeIgG
Storage Buffer50% Glycerol, PBS with 0.02% sodium azide, pH7.3.Purification MethodAffinity purification
Positive SamplesSW620ApplicationELISA, WB

Immunogen Information


Immunogen DescriptionRecombinant fusion protein containing a sequence corresponding to amino acids 604-903 of human CNTROB (NP_444279.2).Target SpeciesHuman
Uniprot IDQ8N137Immunogen Sequence
Background Information
  • Uniprot Id

    Q8N137

  • Target Species

    Human

  • Target Name

    CNTROB

  • Target Full Name

    Centrobin

  • Target Function

    Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.

  • Target Subcellular Location

    Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Centriole-associated, asymmetrically localizes to the daughter centriole.

  • Target Tissue Specificity

    Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.

  • Target Synonyms

    9830165K03Rik; Centrobin; centrobin; centrosomal BRCA2 interacting protein; Centrosomal BRCA2 interacting protein; Centrosomal BRCA2-interacting protein; CNTRB_HUMAN; Cntrob; LIP8; LYST interacting protein 8; LYST-interacting protein 8; LYST-interacting protein LIP8; PP1221; RGD1307488; RP23 26L6.9

  • Target Background

    This gene encodes a centrosomal protein that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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