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The antibody against CNTROB was raised in rabbit using the Fusion protein of Human CNTROB as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
The antibody against CNTROB was raised in rabbit using the Fusion protein of Human CNTROB as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB.
$299.00
| Cat.No | ADC-30326A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CNTROB |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.05% NaN3, 40% Glycerol., pH7.4 PBS |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Fusion protein of Human CNTROB | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q8N137 |
Uniprot Id
Q8N137
Target Species
Human
Target Name
CNTROB
Target Full Name
Centrobin
Target Function
Required for centriole duplication. Inhibition of centriole duplication leading to defects in cytokinesis.
Target Subcellular Location
Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole. Note=Centriole-associated, asymmetrically localizes to the daughter centriole.
Target Tissue Specificity
Widely expressed (at protein level). Highly expressed in testis. Also expressed in spleen, thymus, prostate, small intestine, colon and peripheral blood leukocytes.
Target Synonyms
9830165K03Rik; Centrobin; centrobin; centrosomal BRCA2 interacting protein; Centrosomal BRCA2 interacting protein; Centrosomal BRCA2-interacting protein; CNTRB_HUMAN; Cntrob; LIP8; LYST interacting protein 8; LYST-interacting protein 8; LYST-interacting protein LIP8; PP1221; RGD1307488; RP23 26L6.9
Target Background
This gene encodes a centrosomal protein that interacts with BRCA2, and is required for centriole duplication and cytokinesis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
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