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The antibody against COL12A1 was raised in rabbit using the Recombinant Human Collagen alpha-1(XII) chain protein (140-316AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against COL12A1 was raised in rabbit using the Recombinant Human Collagen alpha-1(XII) chain protein (140-316AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human skeletal muscle tissue using COL12A1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human lung tissue using COL12A1 Antibody at dilution of 1:1002
| Cat.No | ADC-18495A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COL12A1 |
| Target Synonyms | COL12A1 antibody; COL12A1LCollagen alpha-1(XII) chain antibody | Form | Liquid |
| Species Reactivity | Human | Isotype | IgG |
| Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 | Purification Method | >95%, Protein G purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC |
| Storage | Upon receipt |
| Immunogen Description | Recombinant Human Collagen alpha-1(XII) chain protein (140-316AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q99715 |
Uniprot Id
Q99715
Target Species
Human
Target Name
COL12A1
Target Full Name
Collagen alpha-1(XII) chain
Target Function
Type XII collagen interacts with type I collagen-containing fibrils, the COL1 domain could be associated with the surface of the fibrils, and the COL2 and NC3 domains may be localized in the perifibrillar matrix.
Target Involvement
Ullrich congenital muscular dystrophy 2 (UCMD2); Bethlem myopathy 2 (BTHLM2)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix.
Target Protein Families
Fibril-associated collagens with interrupted helices (FACIT) family
Target Tissue Specificity
Found in collagen I-containing tissues: both isoform 1 and isoform 2 appear in amnion, chorion, skeletal muscle, small intestine, and in cell culture of dermal fibroblasts, keratinocytes and endothelial cells. Only isoform 2 is found in lung, placenta, ki
Target Research Area
Signal Transduction
Target Synonyms
COL12A1; COL12A1LCollagen alpha-1(XII) chain
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