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The antibody against COL25A1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human COL25A1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against COL25A1 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human COL25A1. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
$167.00
| Cat.No | ADC-33561A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COL25A1 |
| Form | Liquid | Species Reactivity | Human, Mouse |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from the Internal region of Human COL25A1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9BXS0 |
Uniprot Id
Q9BXS0
Target Species
Human
Target Name
COL25A1
Target Full Name
Collagen alpha-1(XXV) chain
Target Function
Inhibits fibrillization of amyloid-beta peptide during the elongation phase. Has also been shown to assemble amyloid fibrils into protease-resistant aggregates. Binds heparin.
Target Involvement
Fibrosis of extraocular muscles, congenital, 5 (CFEOM5)
Target Subcellular Location
Membrane; Single-pass type II membrane protein. Note=After proteolytic cleavage, CLAC is secreted.
Target Tissue Specificity
Expressed predominantly in brain. Deposited preferentially in primitive or neuritic amyloid plaques which are typical of Alzheimer disease.
Target Synonyms
COL25A1Collagen alpha-1(XXV) chain; Alzheimer disease amyloid-associated protein; AMY; CLAC-P) [Cleaved into: Collagen-like Alzheimer amyloid plaque component; CLAC)]
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