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The antibody against COL6A2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 720-1019 of human COL6A2 (NP_001840.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against COL6A2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 720-1019 of human COL6A2 (NP_001840.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-08799A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COL6A2 |
| Target Synonyms | UCMD1; BTHLM1; PP3610; COL6A2 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, HT-1080, LO2, Mouse lung, SKOV3, THP-1 | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 720-1019 of human COL6A2 (NP_001840.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | P12110 | Immunogen Sequence |
Uniprot Id
P12110
Target Species
Human
Target Name
COL6A2
Target Full Name
Collagen alpha-2(VI) chain
Target Function
Collagen VI acts as a cell-binding protein.
Target Involvement
Bethlem myopathy 1 (BTHLM1); Ullrich congenital muscular dystrophy 1 (UCMD1); Myosclerosis autosomal recessive (MYOSAR)
Target Subcellular Location
Secreted, extracellular space, extracellular matrix. Membrane; Peripheral membrane protein. Note=Recruited on membranes by CSPG4.
Target Protein Families
Type VI collagen family
Target Research Area
Signal Transduction
Target Synonyms
CO6A2_HUMAN; COL6A2; Collagen alpha 2(VI) chain; Collagen alpha-2(VI) chain; collagen type VI alpha 2; Collagen VI alpha 2 polypeptide; human mRNA for collagen VI alpha 2 C terminal globular domain; PP3610
Target Background
This gene encodes one of the three alpha chains of type VI collagen, a beaded filament collagen found in most connective tissues. The product of this gene contains several domains similar to von Willebrand Factor type A domains. These domains have been shown to bind extracellular matrix proteins, an interaction that explains the importance of this collagen in organizing matrix components. Mutations in this gene are associated with Bethlem myopathy and Ullrich scleroatonic muscular dystrophy. Three transcript variants have been identified for this gene.
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