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Rabbit anti-Human COL8A2 Polyclonal Antibody

The antibody against COL8A2 was raised in rabbit using the Synthesized peptide derived from Human COL8A2. at AA range: 611-660 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

ADC-12924A

The antibody against COL8A2 was raised in rabbit using the Synthesized peptide derived from Human COL8A2. at AA range: 611-660 as the immunogen. This antibody exists as a non-conjugated antibody. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, ELISA.

$167.00

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Specifications


Cat.No ADC-12924A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCOL8A2
Target SynonymsCOL8A2Collagen alpha-2(VIII) chain antibody; Endothelial collagen antibodyFormLiquid
Species ReactivityHuman, Mouse, RatStorage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol
Purification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.ConjugateNon-conjugated
ApplicationELISA, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from Human COL8A2. at AA range: 611-660Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP25067
Background Information
  • Uniprot Id

    P25067

  • Target Species

    Human

  • Target Name

    COL8A2

  • Target Full Name

    Collagen alpha-2(VIII) chain

  • Target Function

    Macromolecular component of the subendothelium. Major component of the Descemet's membrane (basement membrane) of corneal endothelial cells. Also component of the endothelia of blood vessels. Necessary for migration and proliferation of vascular smooth muscle cells and thus, has a potential role in the maintenance of vessel wall integrity and structure, in particular in atherogenesis.

  • Target Involvement

    Corneal dystrophy, Fuchs endothelial, 1 (FECD1); Corneal dystrophy, posterior polymorphous, 2 (PPCD2)

  • Target Subcellular Location

    Secreted, extracellular space, extracellular matrix, basement membrane.

  • Target Tissue Specificity

    Expressed primarily in the subendothelium of large blood vessels. Also expressed in arterioles and venules in muscle, heart, kidney, spleen, umbilical cord, liver and lung and is also found in connective tissue layers around hair follicles, around nerve b

  • Target Synonyms

    COL8A2Collagen alpha-2(VIII) chain; Endothelial collagen

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