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The antibody against COPG2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 542-871 of human COPG2 (NP_036265.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against COPG2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 542-871 of human COPG2 (NP_036265.3) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-04815A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | COPG2 |
| Target Synonyms | 2-COP; gamma-2-COP; COPG2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, OVCAR3, U-251MG | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 542-871 of human COPG2 (NP_036265.3). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UBF2 | Immunogen Sequence |
Uniprot Id
Q9UBF2
Target Species
Human
Target Name
COPG2
Target Full Name
Coatomer subunit gamma-2
Target Function
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.
Target Subcellular Location
Cytoplasm, cytosol. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle, COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side.
Target Protein Families
COPG family
Target Synonyms
2 COP; Coat protein nonclathrin gamma 2 cop; Coatomer protein complex subunit gamma 2; Coatomer subunit gamma 2; Coatomer subunit gamma-2; COPG 2; Copg2; COPG2_HUMAN; DKFZp761N09121; FLJ11781; Gamma 2 coat protein; Gamma 2 COP; Gamma-2-coat protein; Gamma-2-COP
Target Background
Predicted to enable structural molecule activity. Involved in intra-Golgi vesicle-mediated transport. Part of COPI vesicle coat.
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