Rabbit anti-Human COQ7 Polyclonal Antibody

The antibody against COQ7 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 37-217 of human COQ7 (NP_057222.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-00059A

Number

Cat.No	ADA-00059A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	COQ7
Target Synonyms	CAT5; CLK1; CLK-1; COQ10D8; COQ7	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse heart, Rat heart, HepG2, MCF7, Mouse liver	Application	ELISA, WB

Cat.No

ADA-00059A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

COQ7

Target Synonyms

CAT5; CLK1; CLK-1; COQ10D8; COQ7

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse heart, Rat heart, HepG2, MCF7, Mouse liver

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 37-217 of human COQ7 (NP_057222.2).	Target Species	Human
Immunogen Sequence	SGMTLDNISRAAVDRIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKDHLKKFNELMVTFRVRPTVLMPLWNVLGFALGAGTALLGKEGAMACTVAVEESIAHHYNNQIRTLMEEDPEKYEELLQLIKKFRDEELEHHDIGLDHDAELAPAYAVLKSIIQAGCRVAIYLSERL	Uniprot ID	Q99807

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 37-217 of human COQ7 (NP_057222.2).

Target Species

Human

Immunogen Sequence

SGMTLDNISRAAVDRIIRVDHAGEYGANRIYAGQMAVLGRTSVGPVIQKMWDQEKDHLKKFNELMVTFRVRPTVLMPLWNVLGFALGAGTALLGKEGAMACTVAVEESIAHHYNNQIRTLMEEDPEKYEELLQLIKKFRDEELEHHDIGLDHDAELAPAYAVLKSIIQAGCRVAIYLSERL

Uniprot ID

Q99807

Background Information

Uniprot Id

Q99807
Target Species

Human
Target Name

COQ7
Target Full Name

5-demethoxyubiquinone hydroxylase, mitochondrial
Target Function

Catalyzes the hydroxylation of 2-polyprenyl-3-methyl-6-methoxy-1,4-benzoquinol (DMQH2) during ubiquinone biosynthesis. Has also a structural role in the COQ enzyme complex, stabilizing other COQ polypeptides. Involved in lifespan determination in a ubiquinone-independent manner.
Target Involvement

Coenzyme Q10 deficiency, primary, 8 (COQ10D8)
Target Subcellular Location

Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Target Protein Families

COQ7 family
Target Tissue Specificity

Expressed dominantly in heart and skeletal muscle.
Target Synonyms

COQ7; 5-demethoxyubiquinone hydroxylase; mitochondrial; DMQ hydroxylase; EC 1.14.13.-; Timing protein clk-1 homolog; Ubiquinone biosynthesis monooxygenase COQ7
Target Background

The protein encoded by this gene is similar to a mitochondrial di-iron containing hydroxylase in Saccharomyces cerevisiae that is involved with ubiquinone biosynthesis. Mutations in the yeast gene lead to slower development and longer life span. Alternatively spliced transcript variants have been found for this gene.

Rabbit anti-Human COQ7 Polyclonal Antibody

Specifications

Immunogen Information

Inquire Rabbit anti-Human COQ7 Polyclonal Antibody Now

Related Products