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Rabbit anti-Human CPOX Polyclonal Antibody

The antibody against CPOX was raised in rabbit using the Human CPOX as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-48871A

The antibody against CPOX was raised in rabbit using the Human CPOX as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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High Purity LevelsPrecision and ReliabilityCustomization Options

Specifications


Cat.No ADC-48871A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCPOX
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman CPOXTarget SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP36551
Background Information
  • Uniprot Id

    P36551

  • Target Species

    Human

  • Target Name

    CPOX

  • Target Full Name

    Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial

  • Target Function

    Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.

  • Target Involvement

    Hereditary coproporphyria (HCP)

  • Target Subcellular Location

    Mitochondrion intermembrane space.

  • Target Protein Families

    Aerobic coproporphyrinogen-III oxidase family

  • Target Synonyms

    Coprogen oxidase; COPROPORPHYRIA; Coproporphyrinogen III oxidase; Coproporphyrinogen Oxidase (CPOX); Coproporphyrinogen-III oxidase; Coproporphyrinogenase; COX; CPO; Cpox; CPX; HEM 6; Hem-6; Hem6; HEM6_HUMAN; mitochondrial

  • Target Background

    The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).

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