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The antibody against CPOX was raised in rabbit using the Human CPOX as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against CPOX was raised in rabbit using the Human CPOX as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-48871A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CPOX |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat |
| Isotype | IgG | Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Human CPOX | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P36551 |
Uniprot Id
P36551
Target Species
Human
Target Name
CPOX
Target Full Name
Oxygen-dependent coproporphyrinogen-III oxidase, mitochondrial
Target Function
Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen-IX.
Target Involvement
Hereditary coproporphyria (HCP)
Target Subcellular Location
Mitochondrion intermembrane space.
Target Protein Families
Aerobic coproporphyrinogen-III oxidase family
Target Synonyms
Coprogen oxidase; COPROPORPHYRIA; Coproporphyrinogen III oxidase; Coproporphyrinogen Oxidase (CPOX); Coproporphyrinogen-III oxidase; Coproporphyrinogenase; COX; CPO; Cpox; CPX; HEM 6; Hem-6; Hem6; HEM6_HUMAN; mitochondrial
Target Background
The protein encoded by this gene is the sixth enzyme of the heme biosynthetic pathway. The encoded enzyme is soluble and found in the intermembrane space of mitochondria. This enzyme catalyzes the stepwise oxidative decarboxylation of coproporphyrinogen III to protoporphyrinogen IX, a precursor of heme. Defects in this gene are a cause of hereditary coproporphyria (HCP).
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