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The antibody against CPT2 was raised in rabbit using the Recombinant Human Carnitine O-palmitoyltransferase 2, mitochondrial protein (388-551AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CPT2 was raised in rabbit using the Recombinant Human Carnitine O-palmitoyltransferase 2, mitochondrial protein (388-551AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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| Cat.No | ADC-08047A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CPT2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Carnitine O-palmitoyltransferase 2, mitochondrial protein (388-551AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P23786 |
Uniprot Id
P23786
Target Species
Human
Target Name
CPT2
Target Full Name
Carnitine O-palmitoyltransferase 2, mitochondrial
Target Function
Involved in the intramitochondrial synthesis of acylcarnitines from accumulated acyl-CoA metabolites. Reconverts acylcarnitines back into the respective acyl-CoA esters that can then undergo beta-oxidation, an essential step for the mitochondrial uptake of long-chain fatty acids and their subsequent beta-oxidation in the mitochondrion. Active with medium (C8-C12) and long-chain (C14-C18) acyl-CoA esters.
Target Involvement
Carnitine palmitoyltransferase 2 deficiency, myopathic, stress-induced (CPT2D); Carnitine palmitoyltransferase 2 deficiency, infantile (CPT2DI); Carnitine palmitoyltransferase 2 deficiency, lethal neonatal (CPT2DLN); Encephalopathy, acute, infection-induced, 4 (IIAE4)
Target Subcellular Location
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.
Target Protein Families
Carnitine/choline acetyltransferase family
Target Research Area
Cancer
Target Synonyms
Carnitine O palmitoyltransferase 2; Carnitine O palmitoyltransferase 2 mitochondrial; Carnitine O-palmitoyltransferase 2; Carnitine palmitoyltransferase 2; Carnitine palmitoyltransferase II; CPT 1; CPT 2; CPT II; CPT1; CPT2; CPT2_HUMAN; CPTASE; CPTII; IIAE4; mitochondrial
Target Background
The protein encoded by this gene is a nuclear protein which is transported to the mitochondrial inner membrane. Together with carnitine palmitoyltransferase I, the encoded protein oxidizes long-chain fatty acids in the mitochondria. Defects in this gene are associated with mitochondrial long-chain fatty-acid (LCFA) oxidation disorders.
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