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Rabbit anti-Human CRABP2 Polyclonal Antibody

The antibody against CRABP2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CRABP-II. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

ADC-38962A

The antibody against CRABP2 was raised in rabbit using the Synthesized peptide derived from the Internal region of Human CRABP-II. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, ELISA.

$167.00

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Specifications


Cat.No ADC-38962A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCRABP2
Target Synonymscellular, type II antibodyFormLiquid
Species ReactivityHuman, Mouse, RatIsotypeIgG
Storage Buffer0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerolPurification MethodThe antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
ConjugateNon-conjugatedApplicationELISA, IHC, WB
StorageUpon receipt

Immunogen Information


Immunogen DescriptionSynthesized peptide derived from the Internal region of Human CRABP-II.Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDP29373
Background Information
  • Uniprot Id

    P29373

  • Target Species

    Human

  • Target Name

    CRABP2

  • Target Full Name

    Cellular retinoic acid-binding protein 2

  • Target Function

    Transports retinoic acid to the nucleus. Regulates the access of retinoic acid to the nuclear retinoic acid receptors.

  • Target Subcellular Location

    Cytoplasm. Endoplasmic reticulum. Nucleus. Note=Upon ligand binding, a conformation change exposes a nuclear localization motif and the protein is transported into the nucleus.

  • Target Protein Families

    Calycin superfamily, Fatty-acid binding protein (FABP) family

  • Target Synonyms

    Cellular retinoic acid binding protein 2; Cellular retinoic acid binding protein II; Cellular retinoic acid-binding protein 2; Cellular retinoic acid-binding protein II; CRABP II; CRABP-II; Crabp2; CRABPII; RABP2_HUMAN; RBP6; Rretinoic acid-binding protein, cellular, type II

  • Target Background

    This gene encodes a member of the retinoic acid (RA, a form of vitamin A) binding protein family and lipocalin/cytosolic fatty-acid binding protein family. The protein is a cytosol-to-nuclear shuttling protein, which facilitates RA binding to its cognate receptor complex and transfer to the nucleus. It is involved in the retinoid signaling pathway, and is associated with increased circulating low-density lipoprotein cholesterol. Alternatively spliced transcript variants encoding the same protein have been found for this gene.

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