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The antibody against CRKL was raised in rabbit using the Synthesized peptide derived from Human Crk-L around the non-phosphorylation site of Y207. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
The antibody against CRKL was raised in rabbit using the Synthesized peptide derived from Human Crk-L around the non-phosphorylation site of Y207. as the immunogen. This antibody exists as a non-conjugated isotype IgG. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on WB, IHC, IF, ELISA.
$167.00
Western Blot analysis of COS7 cells using Crk-L Polyclonal Antibody
| Cat.No | ADC-38952A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CRKL |
| Form | Liquid | Species Reactivity | Human, Mouse, Rat, Monkey |
| Isotype | IgG | Storage Buffer | 0.5% BSA and 0.02% sodium azide., Liquid in PBS containing 50% glycerol |
| Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. | Conjugate | Non-conjugated |
| Application | ELISA, IF, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from Human Crk-L around the non-phosphorylation site of Y207. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P46109 |
Uniprot Id
P46109
Target Species
Human
Target Name
CRKL
Target Full Name
Crk-like protein
Target Function
May mediate the transduction of intracellular signals.
Target Protein Families
CRK family
Target Synonyms
Crk L; Crk like protein; Crk-like protein; Crkl; CRKL_HUMAN; Crkol; HGNC:2363 ; Oncogene CrkL; V crk avian sarcoma virus CT10 oncogene homolog like; v crk sarcoma virus CT10 oncogene homolog (avian) like; V crk sarcoma virus CT10 oncogene homolog avian like
Target Background
This gene encodes a protein kinase containing SH2 and SH3 (src homology) domains which has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase, plays a role in fibroblast transformation by BCR-ABL, and may be oncogenic.
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