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The antibody against CSDE1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 369-600 of human CSDE1 (NP_009089.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, IP, ELISA.
The antibody against CSDE1 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 369-600 of human CSDE1 (NP_009089.4) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IF/ICC, IP, ELISA.
| Cat.No | ADA-16496A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CSDE1 |
| Target Synonyms | UNR; D1S155E; E1 | Form | Liquid |
| Species Reactivity | Human, Mouse | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa | Application | ELISA, WB, IF/ICC, IP |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 369-600 of human CSDE1 (NP_009089.4). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | O75534 | Immunogen Sequence |
Uniprot Id
O75534
Target Species
Human
Target Name
CSDE1
Target Full Name
Cold shock domain-containing protein E1
Target Function
RNA-binding protein involved in translationally coupled mRNA turnover. Implicated with other RNA-binding proteins in the cytoplasmic deadenylation/translational and decay interplay of the FOS mRNA mediated by the major coding-region determinant of instability (mCRD) domain. Required for efficient formation of stress granules.; (Microbial infection) Required for internal initiation of translation of human rhinovirus RNA.
Target Subcellular Location
Cytoplasm. Cytoplasm, Stress granule. Cytoplasm, P-body.
Target Research Area
Epigenetics and Nuclear Signaling
Target Synonyms
Cold shock domain containing E1 RNA binding; Cold shock domain containing protein E1; Cold shock domain-containing protein E1; Csde1; CSDE1_HUMAN; D1S155E; DKFZp779B0247; DKFZp779J1455; FLJ26882; N-ras upstream gene protein; NRAS related; Nras upstream gene protein; NRU; Protein UNR; RP5 1000E10.3; UNR; UNR protein; Upstream of NRAS
Target Background
Enables RNA stem-loop binding activity. Involved in IRES-dependent viral translational initiation; nuclear-transcribed mRNA catabolic process, no-go decay; and stress granule assembly. Located in Golgi apparatus; cytosol; and plasma membrane. Part of CRD-mediated mRNA stability complex.
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