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The antibody against CSRP2 was raised in rabbit using the Recombinant Human Cysteine and glycine-rich protein 2 protein (2-193AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
The antibody against CSRP2 was raised in rabbit using the Recombinant Human Cysteine and glycine-rich protein 2 protein (2-193AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, purified by protein G with a purity greater than 95%. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human umbilical cord tissue using CSRP2 Antibody at dilution of 1:100
| Cat.No | ADC-54268A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CSRP2 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 0.01M PBS, 0.03% Proclin 300; Constituents: 50% Glycerol, PH 7.4 |
| Purification Method | >95%, Protein G purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human Cysteine and glycine-rich protein 2 protein (2-193AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q16527 |
Uniprot Id
Q16527
Target Species
Human
Target Name
CSRP2
Target Full Name
Cysteine and glycine-rich protein 2
Target Function
Drastically down-regulated in response to PDGF-BB or cell injury, that promote smooth muscle cell proliferation and dedifferentiation. Seems to play a role in the development of the embryonic vascular system.
Target Subcellular Location
Nucleus.
Target Tissue Specificity
Highly expressed in the aorta, but not in heart and skeletal muscle.
Target Synonyms
CRP2; CSRP2; CSRP2_HUMAN; Cysteine and glycine rich protein 2; Cysteine and glycine-rich protein 2; Cysteine rich protein 2; Cysteine-rich protein 2; LIM domain only protein 5; LMO-5; LMO5; SmLIM; Smooth muscle cell LIM protein
Target Background
CSRP2 is a member of the CSRP family of genes, encoding a group of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. CRP2 contains two copies of the cysteine-rich amino acid sequence motif (LIM) with putative zinc-binding activity, and may be involved in regulating ordered cell growth. Other genes in the family include CSRP1 and CSRP3. Alternative splicing results in multiple transcript variants.
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