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The antibody against CSTF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human CSTF2 (NP_001316.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
The antibody against CSTF2 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human CSTF2 (NP_001316.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.
| Cat.No | ADA-10694A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CSTF2 |
| Target Synonyms | CstF-64; CSTF2 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | HeLa, HepG2, Jurkat, Mouse testis, Mouse thymus, SW620 | Application | ELISA, WB, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human CSTF2 (NP_001316.1). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | MAGLTVRDPAVDRSLRSVFVGNIPYEATEEQLKDIFSEVGPVVSFRLVYDRETGKPKGYGFCEYQDQETALSAMRNLNGREFSGRALRVDNAASEKNKEELKSLGTGAPVIESPYGETISPEDAPESISKAVASLPPEQMFELMKQMKLCVQNSPQEARNMLLQNPQLAYALLQAQVVMR | Uniprot ID | P33240 |
Uniprot Id
P33240
Target Species
Human
Target Name
CSTF2
Target Full Name
Cleavage stimulation factor subunit 2
Target Function
One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs.
Target Subcellular Location
Nucleus. Note=Localized with DDX1 in cleavage bodies.
Target Synonyms
betaCstF 64 variant 2; CF-1 64 kDa subunit; CF1 64 kDa subunit; Cleavage stimulation factor 2; Cleavage stimulation factor 64 kDa subunit; Cleavage stimulation factor subunit 2; Cleavage stimulation factor; 3' pre RNA; subunit 2; 64kDa; CSTF 2; CstF 64; CSTF 64 kDa subunit; CstF-64; CSTF2; CSTF2_HUMAN; MGC188397
Target Background
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.
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