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The antibody against CTDSP1 was raised in rabbit using the Synthesized peptide derived from N-terminal of Human CTDSP1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
The antibody against CTDSP1 was raised in rabbit using the Synthesized peptide derived from N-terminal of Human CTDSP1. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB, IHC.
$297.00
Western blot analysis of extracts from HUVEC cells and HeLa cells, using CTDSP1 antibody.
Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using CTDSP1 antibody.2
| Cat.No | ADC-41358A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CTDSP1 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, IHC, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from N-terminal of Human CTDSP1. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9GZU7 |
Uniprot Id
Q9GZU7
Target Species
Human
Target Name
CTDSP1
Target Full Name
Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1
Target Function
Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells.
Target Subcellular Location
Nucleus. Note=Colocalizes with RNA polymerase II.
Target Tissue Specificity
Expression is restricted to non-neuronal tissues. Highest expression in skeletal muscle, spleen, lung and placenta.
Target Synonyms
Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 1; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1; CTD (carboxy terminal domain RNA polymerase II polypeptide A) small phosphatase 1; CTD small phosphatase 1; CTDS1_HUMAN; CTDSP1; NIF3; NLI IF ; NLI interacting factor 3; NLI-IF; NLI-interacting factor 3; NLIIF ; Nuclear LIM interactor interacting factor 3; Nuclear LIM interactor-interacting factor 3; SCP1; Small C-terminal domain phosphatase 1; Small CTD phosphatase 1
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