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Rabbit anti-Human CTDSP2 Polyclonal Antibody

The antibody against CTDSP2 was raised in rabbit using the Human CTDSP2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

ADC-46011A

The antibody against CTDSP2 was raised in rabbit using the Human CTDSP2 as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.

$600.00

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Specifications


Cat.No ADC-46011A ClonalityPolyclonal
Host SpeciesRabbitTarget NameCTDSP2
FormLiquidSpecies ReactivityHuman, Mouse, Rat
IsotypeIgGStorage Buffer50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide
Purification MethodAntigen affinity purifiedConjugateNon-conjugated
ApplicationELISA, IHC, WBStorageUpon receipt

Immunogen Information


Immunogen DescriptionHuman CTDSP2Target SpeciesHuman
Immunogen SequenceComplete sequences for the immunogen, target protein, and peptides are available upon request.Uniprot IDO14595
Background Information
  • Uniprot Id

    O14595

  • Target Species

    Human

  • Target Name

    CTDSP2

  • Target Full Name

    Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2

  • Target Function

    Preferentially catalyzes the dephosphorylation of 'Ser-5' within the tandem 7 residue repeats in the C-terminal domain (CTD) of the largest RNA polymerase II subunit POLR2A. Negatively regulates RNA polymerase II transcription, possibly by controlling the transition from initiation/capping to processive transcript elongation. Recruited by REST to neuronal genes that contain RE-1 elements, leading to neuronal gene silencing in non-neuronal cells. May contribute to the development of sarcomas.

  • Target Subcellular Location

    Nucleus.

  • Target Tissue Specificity

    Expression is restricted to non-neuronal tissues. Highest expression in pancreas and lowest in liver.

  • Target Synonyms

    Carboxy terminal domain RNA polymerase II polypeptide A small phosphatase 2; Carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 2; conserved gene amplified in osteosarcoma 4; conserved gene amplified in osteosarcoma; CTDS2_HUMAN; Ctdsp2; NIF2; NLI interacting factor 2; NLI-interacting factor 2; Nuclear LIM interactor interacting factor 2; Nuclear LIM interactor-interacting factor 2; OS4; Protein OS 4; Protein OS-4; PSR2; SCP2; Small C-terminal domain phosphatase 2; Small CTD phosphatase 2

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