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The antibody against CTNNA3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
The antibody against CTNNA3 was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, IF/ICC, ELISA.
| Cat.No | ADA-00225A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CTNNA3 |
| Target Synonyms | VR22; ARVD13; CTNNA3 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.01% thimerosal, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Rat brain, 293T, LO2, Mouse spleen | Application | ELISA, WB, IF/ICC, IHC-P |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1). | Target Species | Human |
|---|---|---|---|
| Uniprot ID | Q9UI47 | Immunogen Sequence |
Uniprot Id
Q9UI47
Target Species
Human
Target Name
CTNNA3
Target Full Name
Catenin alpha-3
Target Function
May be involved in formation of stretch-resistant cell-cell adhesion complexes.
Target Involvement
Arrhythmogenic right ventricular dysplasia, familial, 13 (ARVD13)
Target Subcellular Location
Cytoplasm, cytoskeleton.
Target Protein Families
Vinculin/alpha-catenin family
Target Tissue Specificity
Predominantly expressed in heart and testis. Expressed at lower levels in brain, kidney, liver and skeletal muscle.
Target Synonyms
4930429L08Rik; 4933408A16; Alpha catenin like protein; Alpha T catenin; Alpha T-catenin; Cadherin associated protein ; Cadherin-associated protein; Catenin alpha 3; Catenin alpha-3; Catna3; CTNA3_HUMAN; CTNNA3; MGC26194; MGC75041; OTTHUMP00000019684; OTTMUSP00000028119; OTTMUSP00000028120; RP11-433J16.1; VR22
Target Background
This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants.
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