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The antibody against CTSH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 23-140 of human CTSH (NP_004381.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
The antibody against CTSH was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 23-140 of human CTSH (NP_004381.2) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.
| Cat.No | ADA-03813A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CTSH |
| Target Synonyms | ACC4; ACC5; CPSB; ACC-4; ACC-5; CTSH | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, PBS with 0.05% proclin300, pH7.3. | Purification Method | Affinity purification |
| Positive Samples | Mouse kidney, A-549, HepG2, Mouse liver, Rat kidney, Rat liver | Application | ELISA, WB |
| Immunogen Description | Recombinant fusion protein containing a sequence corresponding to amino acids 23-140 of human CTSH (NP_004381.2). | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | AELCVNSLEKFHFKSWMSKHRKTYSTEEYHHRLQTFASNWRKINAHNNGNHTFKMALNQFSDMSFAEIKHKYLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGS | Uniprot ID | P09668 |
Uniprot Id
P09668
Target Species
Human
Target Name
CTSH
Target Full Name
Pro-cathepsin H
Target Function
Important for the overall degradation of proteins in lysosomes.
Target Subcellular Location
Lysosome.
Target Protein Families
Peptidase C1 family
Target Synonyms
ACC4; ACC5; CPSB; ACC-4; ACC-5; CTSH
Target Background
The protein encoded by this gene is a lysosomal cysteine proteinase important in the overall degradation of lysosomal proteins. It is composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. The encoded protein, which belongs to the peptidase C1 protein family, can act both as an aminopeptidase and as an endopeptidase. Increased expression of this gene has been correlated with malignant progression of prostate tumors. Alternate splicing of this gene results in multiple transcript variants encoding different isoforms.
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