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The antibody against CTU1 was raised in rabbit using the Synthesized peptide derived from C-terminal of Human ATBP3. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
The antibody against CTU1 was raised in rabbit using the Synthesized peptide derived from C-terminal of Human ATBP3. as the immunogen. The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. This antibody has been validated on ELISA, WB.
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Western blot analysis of extracts from LOVO cells, using ATBP3 antibody.
| Cat.No | ADC-41908A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CTU1 |
| Form | Liquid | Species Reactivity | Human |
| Storage Buffer | PH 7.4, 0.02% sodium azide and 50% glycerol., 150mM NaCl, Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+) | Purification Method | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Application | ELISA, WB | Storage | Upon receipt |
| Immunogen Description | Synthesized peptide derived from C-terminal of Human ATBP3. | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q7Z7A3 |
Uniprot Id
Q7Z7A3
Target Species
Human
Target Name
CTU1
Target Full Name
Cytoplasmic tRNA 2-thiolation protein 1
Target Function
Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position.
Target Subcellular Location
Cytoplasm.
Target Protein Families
TtcA family, CTU1/NCS6/ATPBD3 subfamily
Target Synonyms
ATP binding domain 3; ATP-binding domain-containing protein 3; Cancer associated protein; Cancer-associated gene protein; ctu1; CTU1_HUMAN; Cytoplasmic tRNA 2-thiolation protein 1; Cytoplasmic tRNA adenylyltransferase 1; Cytosolic thiouridylase subunit 1 homolog; NCS6
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