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The antibody against CXXC1 was raised in rabbit using the Recombinant Human CXXC-type zinc finger protein 1 protein (1-210AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
The antibody against CXXC1 was raised in rabbit using the Recombinant Human CXXC-type zinc finger protein 1 protein (1-210AA) as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, IHC.
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Immunohistochemistry of paraffin-embedded human colon tissue using CXXC1 Antibody at dilution of 1:100
| Cat.No | ADC-44332A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CXXC1 |
| Form | Liquid | Species Reactivity | Human |
| Isotype | IgG | Storage Buffer | 50% Glycerol, PBS with 0.02% sodium azide, pH7.3. |
| Purification Method | Antigen affinity purified | Conjugate | Non-conjugated |
| Application | ELISA, IHC | Storage | Upon receipt |
| Immunogen Description | Recombinant Human CXXC-type zinc finger protein 1 protein (1-210AA) | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | Q9P0U4 |
Uniprot Id
Q9P0U4
Target Species
Human
Target Name
CXXC1
Target Full Name
CXXC-type zinc finger protein 1
Target Function
Transcriptional activator that exhibits a unique DNA binding specificity for CpG unmethylated motifs with a preference for CpGG.
Target Subcellular Location
Nucleus speckle. Nucleus. Note=Associated with euchromatin. During mitosis, excluded from condensed chromosomes.
Target Tissue Specificity
Ubiquitous.
Target Synonyms
2410002I16Rik; 5830420C16Rik; AI426635; CFP 1; CFP1; CpG binding protein ; CpG-binding protein; CXXC 1; CXXC finger 1; CXXC finger 1 PHD domain; CXXC finger protein 1; CXXC type zinc finger protein 1; CXXC-type zinc finger protein 1; CXXC1; CXXC1_HUMAN; DNA binding protein with PHD finger and CXXC domain ; hCGBP; HsT2645; PCCX 1; PCCX1; PHD finger and CXXC domain containing protein 1; PHD finger and CXXC domain-containing protein 1; PHF 18; PHF18; Protein containing CXXC domain 1; SPP 1; SPP1; ZCGPC 1; ZCGPC1; Zinc finger; CpG binding type containing 1
Target Background
This gene encodes a protein that functions as a transcriptional activator that binds specifically to non-methylated CpG motifs through its CXXC domain. The protein is a component of the SETD1 complex, regulates gene expression and is essential for vertebrate development.
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