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The antibody against CYB5A was raised in rabbit using the Human CYB5A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
The antibody against CYB5A was raised in rabbit using the Human CYB5A as the immunogen. This antibody exists as a non-conjugated isotype IgG, Antigen affinity purified. This antibody has been validated on ELISA, WB, IHC.
$600.00
| Cat.No | ADC-48820A | Clonality | Polyclonal |
|---|---|---|---|
| Host Species | Rabbit | Target Name | CYB5A |
| Target Synonyms | CYB5A; CYB5; Cytochrome b5; Microsomal cytochrome b5 type A; MCB5 | Form | Liquid |
| Species Reactivity | Human, Mouse, Rat | Isotype | IgG |
| Storage Buffer | 50% Glycerol, Avoid freeze / thaw cycles., PBS with 0.1% Sodium Azide | Purification Method | Antigen affinity purified |
| Conjugate | Non-conjugated | Application | ELISA, IHC, WB |
| Storage | Upon receipt |
| Immunogen Description | Human CYB5A | Target Species | Human |
|---|---|---|---|
| Immunogen Sequence | Complete sequences for the immunogen, target protein, and peptides are available upon request. | Uniprot ID | P00167 |
Uniprot Id
P00167
Target Species
Human
Target Name
CYB5A
Target Full Name
Cytochrome b5
Target Function
Cytochrome b5 is a membrane-bound hemoprotein functioning as an electron carrier for several membrane-bound oxygenases.
Target Involvement
Methemoglobinemia CYB5A-related (METHB-CYB5A)
Target Subcellular Location
[Isoform 1]: Endoplasmic reticulum membrane; Single-pass membrane protein; Cytoplasmic side. Microsome membrane; Single-pass membrane protein; Cytoplasmic side.; [Isoform 2]: Cytoplasm.
Target Protein Families
Cytochrome b5 family
Target Synonyms
CYB5A; CYB5; Cytochrome b5; Microsomal cytochrome b5 type A; MCB5
Target Background
The protein encoded by this gene is a membrane-bound cytochrome that reduces ferric hemoglobin (methemoglobin) to ferrous hemoglobin, which is required for stearyl-CoA-desaturase activity. Defects in this gene are a cause of type IV hereditary methemoglobinemia. Three transcript variants encoding different isoforms have been found for this gene.
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