Rabbit anti-Human Cyclophilin B Polyclonal Antibody

The antibody against Cyclophilin B was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 34-216 of human Cyclophilin B (NP_000933.1) as the immunogen. The polyclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, ELISA.

ADA-11020A

Number

Cat.No	ADA-11020A	Clonality	Polyclonal
Host Species	Rabbit	Target Name	Cyclophilin B
Target Synonyms	OI9; CYPB; SCYLP; CYP-S1; HEL-S-39; Cyclophilin B	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, PBS with 0.02% sodium azide, pH7.3.	Purification Method	Affinity purification
Positive Samples	Mouse kidney, 22Rv1, HepG2, MCF7, Mouse brain, Mouse liver, Mouse lung, Rat liver, THP-1	Application	ELISA, WB

Cat.No

ADA-11020A

Clonality

Polyclonal

Host Species

Rabbit

Target Name

Cyclophilin B

Target Synonyms

OI9; CYPB; SCYLP; CYP-S1; HEL-S-39; Cyclophilin B

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, PBS with 0.02% sodium azide, pH7.3.

Purification Method

Affinity purification

Positive Samples

Mouse kidney, 22Rv1, HepG2, MCF7, Mouse brain, Mouse liver, Mouse lung, Rat liver, THP-1

Application

ELISA, WB

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 34-216 of human Cyclophilin B (NP_000933.1).	Target Species	Human
Immunogen Sequence	DEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE	Uniprot ID	P23284

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 34-216 of human Cyclophilin B (NP_000933.1).

Target Species

Human

Immunogen Sequence

DEKKKGPKVTVKVYFDLRIGDEDVGRVIFGLFGKTVPKTVDNFVALATGEKGFGYKNSKFHRVIKDFMIQGGDFTRGDGTGGKSIYGERFPDENFKLKHYGPGWVSMANAGKDTNGSQFFITTVKTAWLDGKHVVFGKVLEGMEVVRKVESTKTDSRDKPLKDVIIADCGKIEVEKPFAIAKE

Uniprot ID

P23284

Background Information

Uniprot Id

P23284
Target Species

Human
Target Name

PPIB
Target Full Name

Peptidyl-prolyl cis-trans isomerase B
Target Function

PPIase that catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and may therefore assist protein folding.
Target Involvement

Osteogenesis imperfecta 9 (OI9)
Target Subcellular Location

Virion.
Target Protein Families

Cyclophilin-type PPIase family, PPIase B subfamily
Target Synonyms

AA408962; AA553318; AI844835; Cphn 2; Cphn2; Cyclophilin B; Cyclophilin like protein; CyP 20b; CYP S1; CYP-S1; CYPB; EC 5.2.1.8; MGC14109; MGC2224; OI9; peptidyl prolyl cis trans isomerase B; Peptidyl prolyl cis trans isomerase B precursor; Peptidyl-prolyl cis-trans isomerase B; peptidylprolyl isomerase B (cyclophilin B); Peptidylprolyl isomerase B; PPIase; PPIase B; Ppib; PPIB_HUMAN; Rotamase; Rotamase B; S cyclophilin; S-cyclophilin; SCYLP
Target Background

The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes, and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta.

Rabbit anti-Human Cyclophilin B Polyclonal Antibody

Specifications

Immunogen Information

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