Rabbit anti-Human DCK Monoclonal Antibody

The antibody against DCK was raised in Rabbit using the recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1) as the immunogen. The monoclonal antibody exists as a isotype IgG, by affinity purification. This antibody has been validated on WB, IHC-P, ELISA.

ADA-15654A

Number

Cat.No	ADA-15654A	Clonality	Monoclonal
Host Species	Rabbit	Target Name	DCK
Target Synonyms	DCK; [KD Validated] DCK	Form	Liquid
Species Reactivity	Human, Mouse, Rat	Isotype	IgG
Storage Buffer	50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.	Purification Method	Affinity purification
Positive Samples	293F, Daudi	Application	ELISA, WB, IHC-P

Cat.No

ADA-15654A

Clonality

Monoclonal

Host Species

Rabbit

Target Name

DCK

Target Synonyms

DCK; [KD Validated] DCK

Form

Liquid

Species Reactivity

Human, Mouse, Rat

Isotype

IgG

Storage Buffer

50% Glycerol, 0.05% BSA, PBS with 0.05% proclin300, pH7.3.

Purification Method

Affinity purification

Positive Samples

293F, Daudi

Application

ELISA, WB, IHC-P

Immunogen Description	Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1).	Target Species	Human
Uniprot ID	P27707	Immunogen Sequence

Immunogen Description

Recombinant fusion protein containing a sequence corresponding to amino acids 1-260 of human DCK (NP_000779.1).

Target Species

Human

Uniprot ID

P27707

Immunogen Sequence

Background Information

Uniprot Id

P27707
Target Species

Human
Target Name

DCK
Target Full Name

Deoxycytidine kinase
Target Function

Phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine. Has broad substrate specificity, and does not display selectivity based on the chirality of the substrate. It is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
Target Subcellular Location

Nucleus.
Target Protein Families

DCK/DGK family
Target Research Area

Cancer
Target Synonyms

dCK; DCK protein; DCK_HUMAN; Deoxycytidine kinase; Deoxynucleoside kinase; EC 2.7.1; EC 2.7.1.74; MGC117410; MGC138632; OTTHUMP00000219118; OTTHUMP00000219119
Target Background

Deoxycytidine kinase (DCK) is required for the phosphorylation of several deoxyribonucleosides and their nucleoside analogs. Deficiency of DCK is associated with resistance to antiviral and anticancer chemotherapeutic agents. Conversely, increased deoxycytidine kinase activity is associated with increased activation of these compounds to cytotoxic nucleoside triphosphate derivatives. DCK is clinically important because of its relationship to drug resistance and sensitivity.

Rabbit anti-Human DCK Monoclonal Antibody

Specifications

Immunogen Information

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